Identification of a Novel Lipofuscin Pigment (iisoA2E) in Retina and Its Effects in the Retinal Pigment Epithelial Cells

Lipofuscin accumulation in retinal pigment epithelial (RPE) cells of the eye implicates the etiologies of Stargardt disease and age-related macular degeneration, a leading cause of blindness in the elderly. Here, we have identified a previously unknown RPE lipofuscin component. By one- and two-dimen...

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Bibliographic Details
Main Authors: Li, Jie, Yao, Ke, Yu, Xiaoning, Dong, Xinran, Gan, Lishe, Luo, Chenqi, Wu, Yalin
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861619/
https://ncbi.nlm.nih.gov/pubmed/24169698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511386
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