Ubiquitination-dependent quality control of hERG K(+) channel with acquired and inherited conformational defect at the plasma membrane

Membrane trafficking in concert with the peripheral quality control machinery plays a critical role in preserving plasma membrane (PM) protein homeostasis. Unfortunately, the peripheral quality control may also dispose of partially or transiently unfolded polypeptides and thereby contribute to the l...

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Huvudupphovsmän: Apaja, Pirjo M., Foo, Brian, Okiyoneda, Tsukasa, Valinsky, William C., Barriere, Herve, Atanasiu, Roxana, Ficker, Eckhard, Lukacs, Gergely L., Shrier, Alvin
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2013
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861077/
https://ncbi.nlm.nih.gov/pubmed/24152733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0417
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