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Trastuzumab emtansine: the first targeted chemotherapy for treatment of breast cancer
Trastuzumab emtansine (T-DM1) is a novel antibody–drug conjugate, comprised of a potent cytotoxic drug connected via a stable linker to the anti-HER2 antibody, trastuzumab, thereby primarily targeting chemotherapy delivery to cells overexpressing the HER2 receptor. A Phase II randomized trial of T-D...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860880/ https://ncbi.nlm.nih.gov/pubmed/23469968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.13.7 |
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