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Trastuzumab emtansine: the first targeted chemotherapy for treatment of breast cancer

Trastuzumab emtansine (T-DM1) is a novel antibody–drug conjugate, comprised of a potent cytotoxic drug connected via a stable linker to the anti-HER2 antibody, trastuzumab, thereby primarily targeting chemotherapy delivery to cells overexpressing the HER2 receptor. A Phase II randomized trial of T-D...

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Bibliografiske detaljer
Main Authors: Peddi, Parvin F, Hurvitz, Sara A
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860880/
https://ncbi.nlm.nih.gov/pubmed/23469968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.13.7
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