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PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancer
The incidence of breast cancer brain metastases has increased in recent years, largely due to improved control of systemic disease with human epidermal growth factor receptor 2 (HER2)-targeted agents and the inability of most of these agents to efficiently cross the blood–blood barrier (BBB) and con...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980725/ https://ncbi.nlm.nih.gov/pubmed/24469856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1369-6 |
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