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PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancer

The incidence of breast cancer brain metastases has increased in recent years, largely due to improved control of systemic disease with human epidermal growth factor receptor 2 (HER2)-targeted agents and the inability of most of these agents to efficiently cross the blood–blood barrier (BBB) and con...

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Bibliografiske detaljer
Main Authors: Peddi, Parvin F., Hurvitz, Sara A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980725/
https://ncbi.nlm.nih.gov/pubmed/24469856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1369-6
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