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Profiling and targeting HER2-positive breast cancer using trastuzumab emtansine
PURPOSE: This article reviews the mechanism of action of trastuzumab emtansine (T-DM1), existing clinical data relating to its use for human growth factor receptor 2 (HER2)-positive breast cancer, potential pathways of resistance, and ongoing studies evaluating this novel agent. BACKGROUND: The deve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207068/ https://ncbi.nlm.nih.gov/pubmed/25378946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S47524 |
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