Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

BACKGROUND: Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate incorporating the human epidermal growth factor receptor 2 (HER2)–targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1. The antibody and the cytotoxic agent are conjuga...

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Bibliographic Details
Published in:N Engl J Med
Main Authors: Verma, Sunil, Miles, David, Gianni, Luca, Krop, Ian E., Welslau, Manfred, Baselga, José, Pegram, Mark, Oh, Do-Youn, Diéras, Véronique, Guardino, Ellie, Fang, Liang, Lu, Michael W., Olsen, Steven, Blackwell, Kim
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125250/
https://ncbi.nlm.nih.gov/pubmed/23020162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1209124
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