Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer

INTRODUCTION: The purpose of this study was to retrospectively explore the relationship between human epidermal growth factor receptor 2 (HER2) messenger RNA (mRNA) expression and efficacy in patients receiving trastuzumab plus docetaxel (HT) or trastuzumab emtansine (T-DM1). METHODS: Patients with...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer Res
Autori principali: Perez, Edith A, Hurvitz, Sara A, Amler, Lukas C, Mundt, Kirsten E, Ng, Vivian, Guardino, Ellie, Gianni, Luca
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229898/
https://ncbi.nlm.nih.gov/pubmed/24887458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3661
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