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Novel approaches to target HER2-positive breast cancer: trastuzumab emtansine
The human epidermal growth factor receptor 2 (HER2) is overexpressed in 20% of breast carcinomas. Prior to the development of targeted therapies, HER2-positive breast cancer was associated with more aggressive disease and poor prognosis. Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate th...
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| Publicado no: | Cancer Manag Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4876844/ https://ncbi.nlm.nih.gov/pubmed/27274311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S104447 |
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