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Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.

The interaction of the hormone erythropoietin and its receptor (EpoR) is though to be required for normal hematopoiesis. To define the role of EpoR in this process, the murine EpoR was disrupted by homologous recombination. Mice lacking the EpoR died in utero at embryonic day 11-12.5 with severe ane...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kieran, M W, Perkins, A C, Orkin, S H, Zon, L I
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38606/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9126
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