Agonistic Antibody to CD40 Boosts the Antitumor Activity of Adoptively Transferred T Cells In Vivo

CD40, a member of the tumor necrosis factor receptor (TNFR) superfamily, is broadly expressed on antigen-presenting cells (APCs) and other cells, including fibroblasts and endothelial cells. Binding of CD40 and its natural ligand CD40L (CD154) triggers cytokine secretion and increased expression of...

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Autori principali: Liu, Chengwen, Lewis, Carol M., Lou, Yanyan, Xu, Chunyu, Peng, Weiyi, Yang, Yan, Gelbard, Alexander H., Lizée, Gregory, Zhou, Dapeng, Overwijk, Willem W., Hwu, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860320/
https://ncbi.nlm.nih.gov/pubmed/22421945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31824e7f43
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