Transduction of Tumor-Specific T Cells with CXCR2 Chemokine Receptor Improves Migration to Tumor and Antitumor Immune Responses

PURPOSE: One of the most important rate-limiting steps in adoptive cell transfer (ACT) is the inefficient migration of T cells to tumors. Since melanomas specifically express the chemokines CXCL1 and CXCL8 that are known to facilitate the CXCR2-dependent migration by monocytes, our aim is to evaluat...

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Main Authors: Peng, Weiyi, Ye, Yang, Rabinovich, Brian A., Liu, Chengwen, Lou, Yanyan, Zhang, Minying, Whittington, Mayra, Yang, Yan, Overwijk, Willem W., Lizée, Gregory, Hwu, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476703/
https://ncbi.nlm.nih.gov/pubmed/20889916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0712
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