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Agonistic Antibody to CD40 Boosts the Antitumor Activity of Adoptively Transferred T Cells In Vivo
CD40, a member of the tumor necrosis factor receptor (TNFR) superfamily, is broadly expressed on antigen-presenting cells (APCs) and other cells, including fibroblasts and endothelial cells. Binding of CD40 and its natural ligand CD40L (CD154) triggers cytokine secretion and increased expression of...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860320/ https://ncbi.nlm.nih.gov/pubmed/22421945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31824e7f43 |
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