Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin

Canonical Wnt (cWnt) signaling through β-catenin regulates osteoblast proliferation and differentiation to enhance bone formation. We previously reported that osteogenic action of β-catenin is dependent on BMP signaling. Here, we further examined interactions between cWnt and BMP in bone. In osteopr...

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Bibliographische Detailangaben
Hauptverfasser: Salazar, Valerie S., Zarkadis, Nicholas, Huang, Lisa, Watkins, Marcus, Kading, Jacqueline, Bonar, Sheri, Norris, Jin, Mbalaviele, Gabriel, Civitelli, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860308/
https://ncbi.nlm.nih.gov/pubmed/24101723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.132233
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