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Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2

Enhanced BMP or canonical Wnt (cWnt) signaling are therapeutic strategies employed to enhance bone formation and fracture repair, but the mechanisms each pathway utilizes to specify cell fate of bone-forming osteoblasts remain poorly understood. Among all BMPs expressed in bone, we find that singula...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Salazar, Valerie S., Ohte, Satoshi, Capelo, Luciane P., Gamer, Laura, Rosen, Vicki
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201040/
https://ncbi.nlm.nih.gov/pubmed/27802170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.136879
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