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Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2

Enhanced BMP or canonical Wnt (cWnt) signaling are therapeutic strategies employed to enhance bone formation and fracture repair, but the mechanisms each pathway utilizes to specify cell fate of bone-forming osteoblasts remain poorly understood. Among all BMPs expressed in bone, we find that singula...

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Publicat a:Development
Autors principals: Salazar, Valerie S., Ohte, Satoshi, Capelo, Luciane P., Gamer, Laura, Rosen, Vicki
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201040/
https://ncbi.nlm.nih.gov/pubmed/27802170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.136879
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