Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche

Two decades after signals controlling bone length were discovered, the endogenous ligands determining bone width remain unknown. We show that postnatal establishment of normal bone width in mice, as mediated by bone-forming activity of the periosteum, requires BMP signaling at the innermost layer of...

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Foilsithe in:eLife
Main Authors: Salazar, Valerie S, Capelo, Luciane P, Cantù, Claudio, Zimmerli, Dario, Gosalia, Nehal, Pregizer, Steven, Cox, Karen, Ohte, Satoshi, Feigenson, Marina, Gamer, Laura, Nyman, Jeffry S, Carey, David J, Economides, Aris, Basler, Konrad, Rosen, Vicki
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2019
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386520/
https://ncbi.nlm.nih.gov/pubmed/30735122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42386
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