β-Catenin and BMP-2 Synergize to Promote Osteoblast Differentiation and New Bone Formation

Mutations of critical components of the Wnt pathway profoundly affect skeletal development and maintenance, probably via modulation of β-catenin signaling. We tested the hypothesis that β-catenin is involved in mesenchymal lineage allocation to osteogenic cells using a β-catenin mutant with constitu...

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Hauptverfasser: Mbalaviele, Gabriel, Sheikh, Sharmin, Stains, Joseph P., Salazar, Valerie S., Cheng, Su-Li, Chen, Di, Civitelli, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647989/
https://ncbi.nlm.nih.gov/pubmed/15526274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.20253
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