Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein.

Cytotoxic T lymphocytes are important effectors of antiviral immunity, and they induce target cell death either by secretion of cytoplasmic granules containing perforin and granzymes or by signaling through the Fas cell surface antigen. Although it is not known whether the granule-mediated and Fas-m...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Macen, J L, Garner, R S, Musy, P Y, Brooks, M A, Turner, P C, Moyer, R W, McFadden, G, Bleackley, R C
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9108
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