Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein.

Cytotoxic T lymphocytes are important effectors of antiviral immunity, and they induce target cell death either by secretion of cytoplasmic granules containing perforin and granzymes or by signaling through the Fas cell surface antigen. Although it is not known whether the granule-mediated and Fas-m...

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Bibliografske podrobnosti
Main Authors: Macen, J L, Garner, R S, Musy, P Y, Brooks, M A, Turner, P C, Moyer, R W, McFadden, G, Bleackley, R C
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC38603/
https://ncbi.nlm.nih.gov/pubmed/8799162
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