Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein.

Cytotoxic T lymphocytes are important effectors of antiviral immunity, and they induce target cell death either by secretion of cytoplasmic granules containing perforin and granzymes or by signaling through the Fas cell surface antigen. Although it is not known whether the granule-mediated and Fas-m...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Macen, J L, Garner, R S, Musy, P Y, Brooks, M A, Turner, P C, Moyer, R W, McFadden, G, Bleackley, R C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9108
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