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Kinetic Mechanism of DNA Polymerization Catalyzed by Human DNA Polymerase ε
Eukaryotes require highly accurate and processive DNA polymerases to ensure faithful and efficient replication of their genomes. DNA polymerase ε (Polε) has been shown to catalyze leading-strand DNA synthesis during replication in vivo, but little is known about the kinetic mechanism of polymerizati...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859840/ https://ncbi.nlm.nih.gov/pubmed/24020356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400803v |
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