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Computational prediction and in vitro analysis of potential physiological ligands of the bile acid binding site in cytochrome c oxidase()

A conserved bile acid site has been crystallographically defined in the membrane domain of mammalian and Rhodobacter sphaeroides cytochrome c oxidase (RsCcO). Diverse amphipathic ligands were shown previously to bind to this site and affect the electron transfer equilibrium between heme a and a(3) c...

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Hlavní autoři: Buhrow, Leann, Hiser, Carrie, Van Voorst, Jeffrey R., Ferguson-Miller, Shelagh, Kuhn, Leslie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859723/
https://ncbi.nlm.nih.gov/pubmed/24073649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400674h
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