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Computational prediction and in vitro analysis of potential physiological ligands of the bile acid binding site in cytochrome c oxidase()
A conserved bile acid site has been crystallographically defined in the membrane domain of mammalian and Rhodobacter sphaeroides cytochrome c oxidase (RsCcO). Diverse amphipathic ligands were shown previously to bind to this site and affect the electron transfer equilibrium between heme a and a(3) c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859723/ https://ncbi.nlm.nih.gov/pubmed/24073649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400674h |
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