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The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain()

Three mutant forms of Rhodobacter sphaeroides cytochrome c oxidase (RsCcO) were created to test for multiple K-path entry sites (E101W), the existence of an “upper ligand site” (M350 W), and the nature and binding specificity of the “lower ligand site” (P315W/E101A) in the region of a crystallograph...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Hiser, Carrie, Liu, Jian, Ferguson-Miller, Shelagh
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078815/
https://ncbi.nlm.nih.gov/pubmed/29626419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2018.03.017
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