KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling

Epigenetic dysregulation has emerged as a major contributor to tumorigenesis. Histone methylation is a well-established mechanism of epigenetic regulation that is dynamically modulated by histone methyltransferases and demethylases. The pathogenic role of histone methylation modifiers in non–small c...

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Detalhes bibliográficos
Main Authors: Wagner, Klaus W., Alam, Hunain, Dhar, Shilpa S., Giri, Uma, Li, Na, Wei, Yongkun, Giri, Dipak, Cascone, Tina, Kim, Jae-Hwan, Ye, Yuanqing, Multani, Asha S., Chan, Chia-Hsin, Erez, Baruch, Saigal, Babita, Chung, Jimyung, Lin, Hui-Kuan, Wu, Xifeng, Hung, Mien-Chie, Heymach, John V., Lee, Min Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859406/
https://ncbi.nlm.nih.gov/pubmed/24200691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68642
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