Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides

IMPORTANCE: Sporadic Alzheimer disease (AD) is caused in part by decreased clearance of the β-amyloid (Aβ) peptide breakdown products. Lipid-depleted (LD) apolipoproteins are less effective at binding and clearing Aβ, and LD Aβ peptides are more toxic to neurons. However, not much is known about the...

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Main Authors: Hanson, Angela J., Bayer-Carter, Jennifer L., Green, Pattie S., Montine, Thomas J., Wilkinson, Charles W., Baker, Laura D., Watson, G. Stennis, Bonner, Laura M., Callaghan, Maureen, Leverenz, James B., Tsai, Elaine, Postupna, Nadia, Zhang, Jing, Lampe, Johanna, Craft, Suzanne
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859238/
https://ncbi.nlm.nih.gov/pubmed/23779114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.396
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