Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides

IMPORTANCE: Sporadic Alzheimer disease (AD) is caused in part by decreased clearance of the β-amyloid (Aβ) peptide breakdown products. Lipid-depleted (LD) apolipoproteins are less effective at binding and clearing Aβ, and LD Aβ peptides are more toxic to neurons. However, not much is known about the...

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Detalhes bibliográficos
Main Authors: Hanson, Angela J., Bayer-Carter, Jennifer L., Green, Pattie S., Montine, Thomas J., Wilkinson, Charles W., Baker, Laura D., Watson, G. Stennis, Bonner, Laura M., Callaghan, Maureen, Leverenz, James B., Tsai, Elaine, Postupna, Nadia, Zhang, Jing, Lampe, Johanna, Craft, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859238/
https://ncbi.nlm.nih.gov/pubmed/23779114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.396
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