Peripheral Amyloid-β Levels Regulate Amyloid-β Clearance from the Central Nervous System

Amyloid-β (Aβ) is cleared from the brain by both proteolytic digestion and transport across the blood-brain-barrier into the peripheral circulatory system. To investigate the role peripheral Aβ levels play in regulating Aβ brain clearance, we measured the clearance of [(125)I]-Aβ(1–40) injected into...

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Huvudupphovsmän: Marques, Marcos A., Kulstad, J. Jacob, Savard, Christopher E., Green, Pattie S., Lee, Sum P., Craft, Suzanne, Watson, G. Stennis, Cook, David G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066174/
https://ncbi.nlm.nih.gov/pubmed/19221422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-0964
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