Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay

Tumor marker endothelial 8 (TEM8) is a receptor for the Protective Antigen (PA) component of anthrax toxin. TEM8 is upregulated on endothelial cells lining the blood vessels within tumors, compared to normal blood vessels. A number of studies have demonstrated a pivotal role for TEM8 in developmenta...

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Detaylı Bibliyografya
Asıl Yazarlar: Cryan, Lorna M., Habeshian, Kaiane A., Caldwell, Thomas P., Morris, Meredith T., Ackroyd, P. Christine, Christensen, Kenneth A., Rogers, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859190/
https://ncbi.nlm.nih.gov/pubmed/23479355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113478655
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