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A FRET Flow Cytometry-Based High Throughput Screening Assay to Identify Disrupters of Glucose Levels in Trypanosoma brucei

Trypanosoma brucei, which causes human African typanosomiasis (HAT), derives cellular ATP from glucose metabolism while in the mammalian host. Targeting glucose uptake or regulation in the parasite has been proposed as a potential therapeutic strategy. However, few methods have been described to ide...

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Publicat a:ACS Infect Dis
Autors principals: Voyton, Charles M., Morris, Meredith T., Ackroyd, P. Christine, Morris, James C., Christensen, Kenneth A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350775/
https://ncbi.nlm.nih.gov/pubmed/29741365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00058
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