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A FRET Flow Cytometry-Based High Throughput Screening Assay to Identify Disrupters of Glucose Levels in Trypanosoma brucei

Trypanosoma brucei, which causes human African typanosomiasis (HAT), derives cellular ATP from glucose metabolism while in the mammalian host. Targeting glucose uptake or regulation in the parasite has been proposed as a potential therapeutic strategy. However, few methods have been described to ide...

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Bibliographic Details
Published in:ACS Infect Dis
Main Authors: Voyton, Charles M., Morris, Meredith T., Ackroyd, P. Christine, Morris, James C., Christensen, Kenneth A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350775/
https://ncbi.nlm.nih.gov/pubmed/29741365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00058
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