1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG) Inhibits Angiogenesis via Inhibition of CMG2

CMG2 is a transmembrane extracellular matrix binding protein that is also an anthrax toxin receptor. We have shown that high affinity CMG2 binders can inhibit angiogenesis and tumor growth. We recently described a high throughput FRET assay to identify CMG2 inhibitors. We now report the serendipitou...

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Detalhes bibliográficos
Main Authors: Cryan, Lorna M., Bazinet, Lauren, Habeshian, Kaiane A., Cao, Shugeng, Clardy, Jon, Christensen, Kenneth A., Rogers, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600088/
https://ncbi.nlm.nih.gov/pubmed/23394144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301558t
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