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Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay
Tumor marker endothelial 8 (TEM8) is a receptor for the Protective Antigen (PA) component of anthrax toxin. TEM8 is upregulated on endothelial cells lining the blood vessels within tumors, compared to normal blood vessels. A number of studies have demonstrated a pivotal role for TEM8 in developmenta...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859190/ https://ncbi.nlm.nih.gov/pubmed/23479355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113478655 |
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