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Ubiquitylation and the Fanconi Anemia Pathway
The Fanconi anemia (FA) pathway maintains genome stability through co-ordination of DNA repair of interstrand crosslinks (ICLs). Disruption of the FA pathway yields hypersensitivity to interstrand crosslinking agents, bone marrow failure and cancer predisposition. Early steps in DNA damage dependent...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858975/ https://ncbi.nlm.nih.gov/pubmed/21605559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.04.078 |
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