Alternative Lengthening of Telomeres: Recurrent Cytogenetic Aberrations and Chromosome Stability under Extreme Telomere Dysfunction

Human tumors using the alternative lengthening of telomeres (ALT) exert high rates of telomere dysfunction. Numerical chromosomal aberrations are very frequent, and structural rearrangements are widely scattered among the genome. This challenging context allows the study of telomere dysfunction-driv...

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Autori principali: Sakellariou, Despoina, Chiourea, Maria, Raftopoulou, Christina, Gagos, Sarantis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858894/
https://ncbi.nlm.nih.gov/pubmed/24339742
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