Alternative Lengthening of Telomeres: Recurrent Cytogenetic Aberrations and Chromosome Stability under Extreme Telomere Dysfunction

Human tumors using the alternative lengthening of telomeres (ALT) exert high rates of telomere dysfunction. Numerical chromosomal aberrations are very frequent, and structural rearrangements are widely scattered among the genome. This challenging context allows the study of telomere dysfunction-driv...

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Main Authors: Sakellariou, Despoina, Chiourea, Maria, Raftopoulou, Christina, Gagos, Sarantis
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858894/
https://ncbi.nlm.nih.gov/pubmed/24339742
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