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Completion of the entire hepatitis C virus life-cycle in genetically humanized mice

More than 130 million people world-wide chronically infected with hepatitis C virus (HCV) are at risk of developing severe liver disease. Antiviral treatments are only partially effective and a vaccine is not available. Development of more efficient therapies has been hampered by the lack of a small...

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Detalhes bibliográficos
Main Authors: Dorner, Marcus, Horwitz, Joshua A., Donovan, Bridget M., Labitt, Rachael N., Budell, William C., Friling, Tamar, Vogt, Alexander, Catanese, Maria Teresa, Satoh, Takashi, Kawai, Taro, Akira, Shizuo, Law, Mansun, Rice, Charles M., Ploss, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858853/
https://ncbi.nlm.nih.gov/pubmed/23903655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12427
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