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Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein
Hepatitis C virus (HCV) contributes substantially to human morbidity and mortality world-wide. The development of HCV genomes expressing heterologous proteins has enhanced the ability to study viral infection, but existing systems have drawbacks. Recombinant viruses often require adaptive mutations...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620014/ https://ncbi.nlm.nih.gov/pubmed/23485372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.01.019 |
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