Effectors of Epidermal Growth Factor Receptor Pathway: The Genetic Profiling of KRAS, BRAF, PIK3CA, NRAS Mutations in Colorectal Cancer Characteristics and Personalized Medicine

Mutations in KRAS oncogene are recognized biomarkers that predict lack of response to anti- epidermal growth factor receptor (EGFR) antibody therapies. However, some patients with KRAS wild-type tumors still do not respond, so other downstream mutations in BRAF, PIK3CA and NRAS should be investigate...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Shen, Yinchen, Wang, Jianfei, Han, Xiaohong, Yang, Hongying, Wang, Shuai, Lin, Dongmei, Shi, Yuankai
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858242/
https://ncbi.nlm.nih.gov/pubmed/24339949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081628
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