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Loss of caveolin-1 expression in knock-in mouse model of Huntington's disease suppresses pathophysiology in vivo
Loss of cholesterol homeostasis and altered vesicle trafficking have been detected in Huntington's disease (HD) cellular and animal models, yet the role of these dysfunctions in pathophysiology of HD is unknown. We demonstrate here that defects in caveolar-related cholesterol trafficking direct...
Tallennettuna:
| Päätekijät: | , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857950/ https://ncbi.nlm.nih.gov/pubmed/24021477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt406 |
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