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PURKINJE CELL DYSFUNCTION AND LOSS IN A KNOCK-IN MOUSE MODEL OF HUNTINGTON DISEASE
Huntington Disease (HD) is an autosomal dominant neurological disorder characterized by motor, psychiatric and cognitive disturbances. Recent evidence indicates that the viability and function of cerebellar Purkinje cells (PCs) are compromised in an aggressive mouse model of HD. Here we investigate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552014/ https://ncbi.nlm.nih.gov/pubmed/23195593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.11.015 |
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