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PURKINJE CELL DYSFUNCTION AND LOSS IN A KNOCK-IN MOUSE MODEL OF HUNTINGTON DISEASE

Huntington Disease (HD) is an autosomal dominant neurological disorder characterized by motor, psychiatric and cognitive disturbances. Recent evidence indicates that the viability and function of cerebellar Purkinje cells (PCs) are compromised in an aggressive mouse model of HD. Here we investigate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dougherty, S.E., Reeves, J. L., Lesort, M., Detloff, P.J., Cowell, R. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552014/
https://ncbi.nlm.nih.gov/pubmed/23195593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.11.015
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