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Epigenetic regulation of the RHOX homeobox gene cluster and its association with human male infertility

The X-linked RHOX cluster encodes a set of homeobox genes that are selectively expressed in the reproductive tract. Members of the RHOX cluster regulate target genes important for spermatogenesis promote male fertility in mice. Studies show that demethylating agents strongly upregulate the expressio...

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Detalles Bibliográficos
Main Authors: Richardson, Marcy E., Bleiziffer, Andreas, Tüttelmann, Frank, Gromoll, Jörg, Wilkinson, Miles F.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857941/
https://ncbi.nlm.nih.gov/pubmed/23943794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt392
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