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The Rhox Homeobox Gene Cluster Is Imprinted and Selectively Targeted for Regulation by Histone H1 and DNA Methylation

Histone H1 is an abundant and essential component of chromatin whose precise role in regulating gene expression is poorly understood. Here, we report that a major target of H1-mediated regulation in embryonic stem (ES) cells is the X-linked Rhox homeobox gene cluster. To address the underlying mecha...

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Autors principals: MacLean, James A., Bettegowda, Anilkumar, Kim, Byung Ju, Lou, Chih-Hong, Yang, Seung-Min, Bhardwaj, Anjana, Shanker, Sreenath, Hu, Zhiying, Fan, Yuhong, Eckardt, Sigrid, McLaughlin, K. John, Skoultchi, Arthur I., Wilkinson, Miles F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067900/
https://ncbi.nlm.nih.gov/pubmed/21245380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-10
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