The Rhox Homeobox Gene Cluster Is Imprinted and Selectively Targeted for Regulation by Histone H1 and DNA Methylation

Histone H1 is an abundant and essential component of chromatin whose precise role in regulating gene expression is poorly understood. Here, we report that a major target of H1-mediated regulation in embryonic stem (ES) cells is the X-linked Rhox homeobox gene cluster. To address the underlying mecha...

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Autores principales: MacLean, James A., Bettegowda, Anilkumar, Kim, Byung Ju, Lou, Chih-Hong, Yang, Seung-Min, Bhardwaj, Anjana, Shanker, Sreenath, Hu, Zhiying, Fan, Yuhong, Eckardt, Sigrid, McLaughlin, K. John, Skoultchi, Arthur I., Wilkinson, Miles F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067900/
https://ncbi.nlm.nih.gov/pubmed/21245380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-10
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