Genome analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of the etiologic agent of tuberculosis

Global spread and genetic monomorphism are hallmarks of Mycobacterium tuberculosis, the agent of human tuberculosis. In contrast, Mycobacterium canettii, and related tubercle bacilli that also cause human tuberculosis and exhibit unusual smooth colony morphology, are restricted to East-Africa. Here,...

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Hauptverfasser: Supply, Philip, Marceau, Michael, Mangenot, Sophie, Roche, David, Rouanet, Carine, Khanna, Varun, Majlessi, Laleh, Criscuolo, Alexis, Tap, Julien, Pawlik, Alexandre, Fiette, Laurence, Orgeur, Mickael, Fabre, Michel, Parmentier, Cécile, Frigui, Wafa, Simeone, Roxane, Boritsch, Eva C., Debrie, Anne-Sophie, Willery, Eve, Walker, Danielle, Quail, Michael A., Ma, Laurence, Bouchier, Christiane, Salvignol, Grégory, Sayes, Fadel, Cascioferro, Alessandro, Seemann, Torsten, Barbe, Valérie, Locht, Camille, Gutierrez, Maria-Cristina, Leclerc, Claude, Bentley, Stephen, Stinear, Timothy P., Brisse, Sylvain, Médigue, Claudine, Parkhill, Julian, Cruveiller, Stéphane, Brosch, Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856870/
https://ncbi.nlm.nih.gov/pubmed/23291586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2517
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