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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation

The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tuberculosis ancestor underwent massive episodes of horiz...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Levillain, Florence, Poquet, Yannick, Mallet, Ludovic, Mazères, Serge, Marceau, Michael, Brosch, Roland, Bange, Franz-Christoph, Supply, Philip, Magalon, Axel, Neyrolles, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720804/
https://ncbi.nlm.nih.gov/pubmed/29176894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006752
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