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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation

The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tuberculosis ancestor underwent massive episodes of horiz...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Levillain, Florence, Poquet, Yannick, Mallet, Ludovic, Mazères, Serge, Marceau, Michael, Brosch, Roland, Bange, Franz-Christoph, Supply, Philip, Magalon, Axel, Neyrolles, Olivier
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720804/
https://ncbi.nlm.nih.gov/pubmed/29176894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006752
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