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Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ(70) domain 1.1
Bacteriophage T7 encodes an essential inhibitor of the Escherichia coli host RNA polymerase (RNAP), the product of gene 2 (Gp2). We determined a series of X-ray crystal structures of E. coli RNAP holoenzyme with or without Gp2. The results define the structure and location of the RNAP σ(70) subunit...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856789/ https://ncbi.nlm.nih.gov/pubmed/24218560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314576110 |
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