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Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ(70) domain 1.1

Bacteriophage T7 encodes an essential inhibitor of the Escherichia coli host RNA polymerase (RNAP), the product of gene 2 (Gp2). We determined a series of X-ray crystal structures of E. coli RNAP holoenzyme with or without Gp2. The results define the structure and location of the RNAP σ(70) subunit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bae, Brian, Davis, Elizabeth, Brown, Daniel, Campbell, Elizabeth A., Wigneshweraraj, Sivaramesh, Darst, Seth A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856789/
https://ncbi.nlm.nih.gov/pubmed/24218560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314576110
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